open access - https://doi.org/10.1016/j.tjnut.2026.101541 Egg Intake and the Incidence of Alzheimer’s Disease in the Adventist Health Study-2 Cohort Linked with Medicare Data
In this health-conscious population, moderate egg consumption was associated with a significantly lower risk of Alzheimer’s disease. These findings suggest a potential neuroprotective benefit of nutrients found in eggs when consumed as part of a balanced diet.
Initial support for the cohort was provided by the National Cancer Institute (grant 1U01CA152939). The analyses in this study were supported by an investigator-initiated grant from the American Egg Board. The funding sources had no role in the study design, execution, data analysis, interpretation, manuscript preparation, or publication.
The authors report no conflicts of interest.
important context the 7th day adventists are a plant based philosophical organization, the initial bias of their observational study AHS-2 would be anti-egg.
Observational epidemiology cannot establish cause and effect, weak hazard ratios are not clinically meaningful, and should only be used to generate hypothesis and design interventional studies.
Observational epidemiology […] should only be used to generate hypothesis and design interventional studies.
I feel like I’ve seen this same thing said at least three times in the past few days. It used to be that we all just went “correlation does not imply causation”. What changed?
There are many people who would rather use correlation to push their philosophy then doing the work of a interventional study.
The risk of doing the actual falsifiable experiment is your hypothesis might be wrong
The effect is very correlative. The more eggs you eat the more likely you are to die before you can get Alzheimer’s.
That’s a joke. I have yard birds and far more eggs than I can safely eat. Eggs are fine in moderation but I’ve seen my blood work. The more eggs the higher my LDL.
No problem with higher LDL by itself.
